There has been a lot of research on the impact of human capital as it applies to organizational performance. Lean management certainly touches on a lot of aspects of human behavior. Resilience engineering has some focus areas related to cognitive bias and certainly the study of Learning Organizations includes a lot human behavior characteristics. In this presentation we are going to look at the vast knowledge of psychological research that could be applied to human capital and organizational performance. We will start by looking at what Dr Deming (everything starts with Deming!) said about psychology and organizational behavior in something he coined as the “System of Profound Knowledge”. We will also look at some of the research done on organizational burnout, whereas some of the symptoms of burnout can actually be used as anti patterns for High-Performance Organizations. We will also look at some other research some of the leaders in the Devops movement have been looking at as clues to optimize organizational performance.